Telomerase a New Fountain of Youth?
August 27th, 2008 admin
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Telomerase is an enzyme that adds specific DNA sequence repeats to the end of DNA strands in the telomere regions. Telomerase consists of two molecules each – telomerase reverse transcriptase (TERT), telomerase RNA (TERC) and dyskerin. By using TERC, TERT can add a specific six-nucleotide repeating sequence to the strand of chromosomes. These repeats are called telomeres. As we get older, the ends of the chromosomes that carry our genes start to erode. Each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide and becomes inactive or “senescent” or dies. This process is associated with aging. Telomeres do not shorten with age, though, in tissues such as heart muscle…
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